Electrical potential difference of colonic mucosa.
نویسندگان
چکیده
منابع مشابه
The Electrical Potential Difference
Studies of the physicochemical forces involved in the transfer of ions and water across biological membranes have received great impetus from the work on the isolated frog skin by Ussing, Zerahn and Koefoed-Johnson (1, 2). This type of approach would help to define the mechanisms involved in the transfer of fluid and electrolyte across the intestine in vivo. A previous study on the large intest...
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Superfusion of canine tracheal mucosa with 100 microg each of grepafloxacin and ciprofloxacin per ml reduced the electrical transepithelial potential difference in vivo by more than 50%. This effect was dose dependent, specific for new quinolones, and inhibited by Cl channel blockers, indicating that new quinolones attenuate Cl secretion across the airway epithelium.
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• Over the past decade, several types of experiments characterizing the electrical properties of blood vessels have been carried out.' 2 Some of these experiments were done to determine the possible existence, magnitude, and polarity of the normal potential difference across the aortic and vena caval wall using in vivo and in vitro preparations." The first group of experiments was done in the l...
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serosal n-butyric acid (O, O,1, 1, or 1O mmollL, adjusted to neutral pH) on the epithelial cell proliferation rate of pig colonic mucosa in organ culture taking crypt cell production rate (CCPR) as the measure of proliferative activity With O or O.1 mmolfL n-butyric acid on the serosal side, luminal n-butyric acid increased CCPR at 1,O mmol/L, and decreased CCPR at 1O mmollL when compared to th...
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OBJECTIVE The study summarizes results of karyometric measurements in epithelial cells of the colorectal mucosa to document evidence of a field effect of preneoplastic development among patients with colorectal adenocarcinoma or adenoma. METHODS Karyometric analyses were done on high-resolution images of histologic sections from 48 patients with colorectal adenocarcinomas and 44 patients with...
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ژورنال
عنوان ژورنال: Gut
سال: 1975
ISSN: 0017-5749
DOI: 10.1136/gut.16.4.315